Citation

Mykkanen S, Ariniemi K, Nummi P, Lillsunde PM. Proc. Int. Counc. Alcohol Drugs Traffic Safety Conf. 2000; 2000: -p..

Copyright

(Copyright © 2000, The author(s) and the Council, Publisher International Council on Alcohol, Drugs and Traffic Safety)

DOI

unavailable

PMID

unavailable

Abstract

A GC-MS (gas chromatography-mass spectrometry) method for simultaneous determination of pholcodine, morphine, codeine, 6-acetylmorphine, dihydrocodeine and ethylmorphine in urine and blood is described. The method employs propionic anhydride in the presence of triethylamine to propionylate free hydroxyl groups of the opiates. Confirmation is achieved using gas chromatography/mass spectrometry in the electron impact mode.