Citation

LaRosa JC. Rev. Esp. Cardiol. 1995; 48(Suppl 2): 14-17.

Vernacular Title

Existe una relacion entre la reduccion del colesterol, los bajos niveles de

Affiliation

George Washington University Medical Center, Washington, DC 20037, USA.

Copyright

(Copyright © 1995, Elsevier Publishing)

DOI

unavailable

PMID

7569270

Abstract

Cholesterol lowering in both primary and secondary prevention has been clearly demonstrated to lower coronary morbidity and, in secondary prevention, to lower coronary mortality as well. Putative dangers of cholesterol lowering remain unproven. Population studies linking low cholesterol to noncoronary mortalities do not demonstrate cause-and-effect relations. In fact, based on current studies, the opposite is more likely to be the case. Neither gender nor age should automatically exclude persons from cholesterol screening. Drug intervention, however, should be used conservatively, particularly in young adults and the elderly. Drugs should be used only after diet and lifestyle interventions have failed. The evidence linking high blood cholesterol to coronary atherosclerosis and cholesterol lowering to its prevention is broad-based and definitive. Concerns about cholesterol lowering and spontaneously low cholesterols should be pursued but should not interfere with the implementation of current public policies to reduce the still heavy burden of atherosclerosis in Western society.

Language: es