Citation

Rivas López FA, López Soriano F, Mendoza Cerezo A, Jiménez Ferré J, Azurmendi Rodríguez JI, de la Rubia Nieto MA. Rev. Esp. Anestesiol. Reanim. 1989; 36(1): 48-50.

Vernacular Title

Intoxicacion benzodiacepinica mixta y reversion por flumacenil (Ro 15-1788).

Copyright

(Copyright © 1989, Sociedad Española de Anestesiología y Reanimación)

DOI

unavailable

PMID

2565591

Abstract

A case of 17 year old female with acute benzodiazepines (800 mg of bentazepan and 400 mg de chlordiazepoxide) and tricyclic antidepressants (500 mg of imipramine) self poisoning is reported. Initial examination showed comatous patient (Glasgow coma scale 7, sedation scale 4) and a critical respiratory failure with a suspicious of pulmonary aspiration of gastric contents. Supportive measures were started and flumazenil administered intravenous (0.1 mg/min) until a total dose of 1.2 mg; 15 minutes later neurological state was absolutely normal. We conclude that flumazenil is a selective and useful benzodiazepine antagonist in the treatment of acute benzodiazepine poisoning.

Language: es