Citation

Zalsman G, Anderson GM, Peskin M, Frisch A, King RA, Vekslerchik M, Sommerfeld E, Michaelovsky E, Sher L, Weizman A, Apter A. J. Neural. Transm. 2005; 112(2): 309-315.

Affiliation

Adolescent Inpatient Department and Research Unit, Geha Mental Health Center, Petach Tikva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. zalsman@columbia.edu

Copyright

(Copyright © 2005, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s00702-004-0244-6

PMID

15657646

Abstract

Relationships between the serotonin transporter promoter polymorphism (5-HTTLPR), platelet serotonin transporter (SERT) binding and clinical phenotype were examined in 32 suicidal and 28 non-suicidal Ashkenazi Israeli adolescent psychiatric inpatients. The 5-HTTLPR polymorphism was not associated with transporter binding or with suicidality or other clinical phenotypes. However, in the suicidal group, a significant positive correlation between platelet SERT density and anger scores (n=32, r=.40; p=.027) and a negative correlation between platelet count and trait anxiety (n=32, r=-.42; p=.034) were observed.

Language: en