Citation

Derry CP. Curr. Neurol. Neurosci. Rep. 2011; 11(2): 218-226.

Affiliation

Department of Clinical Neurosciences, Western General Hospital, Edinburgh, EH4 2XU, UK, cderry@nhs.net.

Copyright

(Copyright © 2011, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s11910-011-0180-4

PMID

21234718

Abstract

Frontal lobe seizures have a tendency to occur from sleep, and in some cases occur exclusively (or almost exclusively) from sleep; these individuals are said to have nocturnal frontal lobe epilepsy (NFLE). NFLE can be difficult to distinguish clinically from various other sleep disorders, particularly parasomnias, which also present with paroxysmal motor activity in sleep. Here, the manifestations of frontal lobe epilepsy are reviewed in detail, with particular reference to the influence of sleep and the characteristics of NFLE. Key aspects of differential diagnosis are also considered, and the underlying mechanisms involved in NFLE discussed.

Language: en