Citation

Scherr M, Schwerthoeffer D, Froboese T, Castrop F, Bäuml J. Fortschr. Neurol. Psychiatr. 2009; 77(10): 585-590.

Vernacular Title

Yohimbin, ein Alpha-2-Antagonist: Literaturubersicht zu psychiatrisch relevanten

Affiliation

Klinik und Poliklinik für Psychiatrie und Psychotherapie, Klinikum rechts der Isar, Technische Universität München. martin_scherr@hotmail.com

Copyright

(Copyright © 2009, Georg Thieme Verlag)

DOI

10.1055/s-0028-1109758

PMID

19821221

Abstract

We describe a 21-year old female patient who had taken the alpha-2-antagonist yohimbine for weight-loss. The patient reported alterations in alcohol- and cocaine-seeking along with changes in defensive behaviour, including suicidal tendencies. Pre-clinical and clinical studies are discussed, which support the hypothesis of a causal relationship. We added an overview of relevant psychiatric effects and side effects of yohimbine.

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