Citation

Kolodzik JM, Eilers MA, Angelos MG. Ann. Emerg. Med. 1990; 19(4): 378-381.

Affiliation

Department of Emergency Medicine, Wright State University, School of Medicine, Dayton, Ohio 45401-0927.

Copyright

(Copyright © 1990, American College of Emergency Physicians, Publisher Elsevier Publishing)

DOI

unavailable

PMID

2321822

Abstract

We present the case of a 17-year-old girl who ingested 24 to 36 g fenoprofen as a suicidal gesture. She presented with coma, hypotension, metabolic acidosis, and respiratory depression within four hours of ingestion. The most common adverse effects of the nonsteroidal anti-inflammatory drugs occur in both therapeutic and toxic doses and include gastrointestinal upset, blood dyscrasias, and analgesic nephropathy. The propionic acid derivatives of nonsteroidal anti-inflammatory drugs, including fenoprofen and ibuprofen, are rarely associated with severe toxic effects. This is the first report of pure fenoprofen overdose presenting as coma and metabolic acidosis.

Language: en