Citation

Roy A, Virkkunen M, Linnoila M. Prog. Neuropsychopharmacol. Biol. Psychiatry 1987; 11(2-3): 173-177.

Copyright

(Copyright © 1987, Elsevier Publishing)

DOI

unavailable

PMID

2442799

Abstract

We review cerebrospinal fluid (CSF) studies suggesting on association between low CSF levels of the serotonin metabolite 5-hydroxyindoleacetic acid (5-HIAAA) and suicidal and impulsive behaviour and alcoholism. Relatively high percentages of alcoholics attempt and commit suicide and have impulsive antisocial personality disorder. Therefore, we suggest that there may be a sizable subgroup of alcoholics who have a reduced central serotonin turnover.

Language: en