Citation

Buckley P, Bartell J, Donenwirth K, Lee S, Torigoe F, Schulz SC. Bull. Am. Acad. Psychiatry Law 1995; 23(4): 607-611.

Affiliation

Northcoast Behavioral Healthcare System, Northfield, OH 44167, USA.

Copyright

(Copyright © 1995, American Academy of Psychiatry and the Law)

DOI

unavailable

PMID

8639988

Abstract

Pharmacological management of persistent aggression in patients with schizophrenia is a difficult clinical dilemma. Clozapine has been shown to be an effective agent in this regard. This study sought to compare the symptomatic response on the Brief Psychiatric Rating Scale (BPRS) between hostile schizophrenic patients and patients without aggression. While dramatic improvements were evident in aggression, both groups were indistinguishable with respect to BPRS response. These results suggest that clozapine may have a selective antiaggressive effect.

Language: en