Citation

Hegeman J, Weerdesteyn V, van den Bemt BJ, Nienhuis B, van Limbeek J, Duysens J. BMC Res. Notes 2010; 3(1): 243.

Copyright

(Copyright © 2010, Holtzbrinck Springer Nature Publishing Group - BMC)

DOI

10.1186/1756-0500-3-243

PMID

20863363

PMCID

PMC2955582

Abstract

BACKGROUND: Alcohol is a commonly used social drug and driving under influence is a well-established risk factor for traffic accidents. To improve road safety, legal limits are set for blood alcohol concentration (BAC) and driving, usually at 0.05% (most European countries) or 0.08% (most US states, Canada and UK). Alcohol, even at these low concentrations, affects brain function and increases fall risk. An increased fall risk has been associated with impaired obstacle avoidance skills. Low level BACs are likely to affect obstacle avoidance reactions during gait, since the brain areas that are presumably involved in these reactions have been shown to be influenced by alcohol. Therefore we investigated the effect of low to moderate alcohol consumption on such reactions. Thirteen healthy senior individuals were subjected to an obstacle avoidance task on a treadmill after low alcohol consumption. Fast stepping adjustments were required to successfully avoid suddenly appearing obstacles. Response times and amplitudes of the m. biceps femoris, a prime mover, as well as avoidance failure rates were assessed. FINDINGS: After the first alcoholic drink, 12 of the 13 participants already had slower responses. Without exception, all participants' biceps femoris response times were delayed after the final alcoholic drink (avg+/-sd:180+/-20ms; p<0.001) compared to when participants were sober (156+/-16ms). Biceps femoris response times were significantly delayed from BACs of 0.035% onwards and were strongly associated with increasing levels of BAC (r=0.6; p<0.001). These delays had important behavioural consequences. Chances of hitting the obstacle were doubled with increased BACs. CONCLUSIONS: The present results clearly show that even with BACs, considered to be safe for driving, obstacle avoidance reactions are inadequate, late, and too small. This is likely to contribute to an increased fall risk. Therefore we suggest that many of the alcohol-related falls are the result of the disruptive effects of alcohol on the online corrections of the ongoing gait pattern when walking under challenging conditions.

Language: en