Citation

Sakuma M, Oinuma T, Endo N. Clin. Calcium 2010; 20(9): 1327-1332.

Affiliation

Department of Physical Therapy, Faculty of Medical Technology, Niigata University of Health and Welfare/Division of Orthopedic Surgery, Department of Regenerative and Transplant Medicine, Niigata University Graduate School of Medical and Dental Science.

Copyright

(Copyright © 2010, Iyanku Journal Company)

DOI

CliCa100913271332

PMID

20808040

Abstract

Although an increase in vitamin D has a small effect on bone mineral density, it has an influence on fracture prevention. This may be explained by a mechanism of improvement of bone strength that does not necessarily depend on bone mineral density. The level of serum 25 (OH) D is low in hip fracture patients compared with non-fracture controls, which suggests that a background of vitamin D insufficiency may be involved in hip fracture. Vitamin D acts on skeletal muscle and nerve cells, and it has been reported that this has an effect on fall prevention. Furthermore, recent reports suggest a role of vitamin D in cognitive function and in other tissues not involving bone.

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