Citation

Serna A, Pigot H, Rialle V. Int. J. Med. Inform. 2007; 76(Suppl 3): S377-83.

Affiliation

TIMC-IMAG UMR CNRS 5525 Laboratory, Grenoble, France. Audrey.Serna@imag.fr

Copyright

(Copyright © 2007, Elsevier Publishing)

DOI

10.1016/j.ijmedinf.2007.04.002

PMID

17513165

Abstract

This article presents a computational model and a simulation of the decrease of performance in daily living activities due to Alzheimer's disease. The framework offered by the cognitive architecture ACT-R is used to develop the model. Typical errors committed in performing tasks by Alzheimer patients are modelled thanks to different parametrisable memory mechanisms of ACT-R and the disease evolution is represented by the increase of errors in the execution of the task. The model is applied to a cooking activity. Simulation of 100 subjects shows results similar to those realised in a standardized assessment with human subjects. We conclude on the need to introduce executive mechanisms in the modelling of behaviours associated to people with cognitive deficits.

Language: en