Citation

Monhart V. Vnitr. Lek. 1997; 43(10): 686-690.

Vernacular Title

Otravy muchomurkami a vyznam sorpcni hemoperfuze pri jejich leceni.

Affiliation

III. interní oddĕlení Ustrední vojenské nemocnice, Praha.

Copyright

(Copyright © 1997, Avicenum)

DOI

unavailable

PMID

9601885

Abstract

Intoxications with poisonous mushrooms, in particular toadstools, are still a serious medical problem. The author presents contemporary views on the etiopathogenesis of intoxications with Amanita phalloides, the clinical picture of the phalloid syndrome and its prognosis. He emphasizes the importance of a comprehensive therapeutic approach, incl. the administration of antidotes (penicillin G and silibinin) and extracorporeal haemoelimination treatment. Early sorption haemoperfusion, either alone or combined with haemodialysis or plasmapheresis, prevent the development of hepatic and renal failure and significantly reduce the mortality from mushroom poisoning. The results of amanitine sorption in in vitro experiments and in the treatment of human intoxications justify the use of biocompatible synthetic resin sorbents (Amberlite XAD-2) in the treatment of mushroom poisoning rather than active charcoal.

Language: cs