Citation

Kolecki PF, Curry SC. Crit. Care Clin. 1997; 13(4): 829-848.

Affiliation

Department of Medical Toxicology, Good Samaritan Regional Medical Center, Phoenix, Arizona, USA.

Copyright

(Copyright © 1997, Elsevier Publishing)

DOI

unavailable

PMID

9330843

Abstract

Poisoning by drugs that block voltage-gated sodium channels produces intraventricular conduction defects, myocardial depression, bradycardia, and ventricular arrhythmias. Human and animal reports suggest that hypertonic sodium bicarbonate may be effective therapy for numerous agents possessing sodium channel blocking properties, including cocaine, quinidine, procainamide, flecainide, mexiletine, bupivacaine, and others.

Language: en