Citation

Keil A, Bradley MM, Ihssen N, Heim S, Vila J, Guerra P, Lang PJ. Neuropsychologia 2010; 48(12): 3580-3584.

Affiliation

NIMH Center for the Study of Emotion and Attention, University of Florida, Gainesville, Florida.

Copyright

(Copyright © 2010, Elsevier Publishing)

DOI

10.1016/j.neuropsychologia.2010.08.007

PMID

20713075

PMCID

PMC2949445

Abstract

We tested whether visual cortical sensitivity to external cues in the context of an acute defensive reaction is heightened or attenuated. A strong cardiac defense (fear) response was elicited by presenting an abrupt, loud acoustic stimulus following a 10-minute period of quiescence. Electrocortical responses to aversive and neutral pictures following defensive stimulus onset were measured using dense-array EEG. Pictures were flickered at 12.5Hz to evoke steady-state visual evoked potentials (ssVEP), which can be reliably extracted on the basis of single trials. Visual cortical activity indexing perceptual processing was substantially heightened when pictures were shown in temporal proximity to (i.e., 5 second after) the defense stimulus. Replicating previous studies, aversive visual stimuli were associated with enhanced ssVEP amplitude, compared to neutral stimuli. Acute defense facilitates visual perception of external cues and preserves accurate discrimination between threatening and safe cues.

Language: en