Citation

Ferreira LA, Alves WE, Lucas MS, Habermehl GG. Toxicon 1996; 34(5): 599-603.

Affiliation

Departamento de Bioquimica e Biofisica, Instituto Butantan, São Paulo, Brazil.

Copyright

(Copyright © 1996, Elsevier Publishing)

DOI

10.1016/0041-0101(96)00010-4

PMID

8783454

Abstract

Venom of the spider Scaptocosa raptoria was fractionated by chromatography on Sephadex G-10 followed by HPLC, and a bradykinin potentiating peptide, BPP-S, was obtained in pure form. The amino acid sequence of this undecapeptide is presented. Peptide BPP-S significantly potentiates the effects of bradykinin on smooth muscle, and inhibits the angiotensin-converting enzyme (ACE) in vitro.

Language: en