Citation

Hantson P, Benaissa M, Clemessy JL, Baud FJ. Intensive Care Med. 1996; 22(5): 453-455.

Affiliation

Réanimation Toxicologique, Hôpital Fernand Widal, Paris, France.

Copyright

(Copyright © 1996, Holtzbrinck Springer Nature Publishing Group)

DOI

unavailable

PMID

8796400

Abstract

We observed a 51-year-old woman who was admitted for severe amitriptyline overdose. Besides major cardiovascular complications, the patient developed severe hyperpyrexia with a central body temperature of more than 43 degrees C for 5 h. The patient died on day 3 from cardiocirculatory collapse and arrhythmias. Hyperthermia was unresponsive to cooling with ice water, gastric lavage, muscle relaxation, and dantrolene and bromocriptine administration. The possible mechanisms of refractory hyperthermia are discussed.

Language: en