Citation

Demirkiran M, Jankovic J, Dean JM. Clin. Neuropharmacol. 1996; 19(2): 157-164.

Affiliation

Department of Neurology, Baylor College of Medicine, Houston, TX 77030, USA.

Copyright

(Copyright © 1996, Lippincott Williams and Wilkins)

DOI

unavailable

PMID

8777769

Abstract

3,4-Methylenedioxymethamphetamine (MDMA), also known as "ecstasy" is a popular recreational drug with potential for abuse. Although its neurotoxic effects have been established in animal studies, the acute and long-term effects of this serotonergic agent in humans are still unknown. We describe a 19-year-old woman with overlapping symptoms of neuroleptic malignant syndrome and serotonin syndrome after a single exposure to MDMA. We also review 15 other cases reported in the literature to draw attention to the serious neurotoxicity, including fatal outcomes, caused by the use of this increasingly popular, illicit drug.

Language: en