Citation

Nimmo SM, Kennedy BW, Tullett WM, Blyth AS, Dougall JR. Anaesthesia 1993; 48(10): 892-895.

Affiliation

Intensive Therapy Unit, Western Infirmary, Glasgow.

Copyright

(Copyright © 1993, Association of Anaesthetists of Great Britain and Ireland, Publisher John Wiley and Sons)

DOI

unavailable

PMID

7902026

Abstract

Drugs with antidopaminergic properties and those capable of stimulating serotonin release can be responsible for hyperthermia syndromes such as neuroleptic malignant syndrome and serotonin syndrome. Dopamine and serotonin are important neurotransmitters in temperature regulation and it is likely that these reactions result from drug-induced changes in neurotransmitter levels. We describe three cases of drug-induced hyperthermia, discuss their aetiology and management, with both general measures and therapies designed to redress neurotransmitter imbalance.

Language: en