Citation

Watson JD, Ferguson CJ, Hinds CJ, Skinner R, Coakley JH. Anaesthesia 1993; 48(12): 1057-1060.

Affiliation

Intensive Care Unit, St. Bartholomew's Hospital at Smithfield, London.

Copyright

(Copyright © 1993, Association of Anaesthetists of Great Britain and Ireland, Publisher John Wiley and Sons)

DOI

unavailable

PMID

7904429

Abstract

There are increasing numbers of patients admitted to hospital as a result of ingesting amphetamine-like drugs. The most severe cases exhibit hyperthermia, rhabdomyolysis, coagulopathy and renal failure. We describe six such patients with varying severity of intoxication, and have reviewed the recent literature with particular reference to the use of dantrolene. One of our patients died but the others all survived. There is little evidence that dantrolene influenced the outcome in patients reported to date. We believe that a controlled trial should be carried out in amphetamine-related hyperthermia before the use of dantrolene becomes widespread.

Language: en