Citation

Köthe L, Radke J. Anaesthesist 2010; 59(6): 529-534.

Vernacular Title

Carboxyhamoglobinkonzentration bei Kohlenmonoxidvergiftung. Kritische Betrachtung

Affiliation

Universitätsklinik für Anästhesiologieund operative Intensivmedizin, Universitätsklinikum Halle/Saale, Ernst-Grube-Str. 40, 06097, Halle/Saale, Deutschland, lars.koethe@medizin.uni-halle.de.

Copyright

(Copyright © 2010, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s00101-010-1730-x

PMID

20442979

Abstract

In cases of unclear depression of conciousness, arrhythmia and symptoms of cardiac insufficiency inadvertent carbon monoxide intoxication should always be taken into consideration. Rapid diagnosis of acute carbon monoxide intoxication with mostly unspecific symptoms requires an immediate supply of high dose oxygen which enables a distinct reduction of mortality and long-term morbidity. Levels of carboxyhemoglobin, however, should not be used as a parameter to decide whether to supply normobaric or the more efficient hyperbaric oxygen. There is no sufficient coherence between carboxyhemoglobin blood levels and clinical symptoms. Increased carboxyhemoglobin concentrations help to diagnose acute carbon monoxide intoxication but do not allow conclusions to be drawn about possible long-term neuropsychiatric or cardiac consequences.

Language: de