Citation

Seton M, Jackson V, Lasser KE, Doppelt S, Pierre-Jacques M, Connelly M. J. Clin. Densitom. 2005; 8(4): 454-460.

Affiliation

Rheumatology, Arthritis and Osteoporosis Center, Cambridge Health Alliance, Cambridge, MA 02139, USA. Margaret_seton@hms.harvard.edu

Copyright

(Copyright © 2005, International Society for Clinical Densitometry, Publisher Elsevier Publishing)

DOI

unavailable

PMID

16311431

Abstract

Ethnic diversity and lower socioeconomic populations are poorly captured in most studies of osteoporosis and fracture risk. This article describes a prospective, observational study designed to analyze risk factors for fracture in an ambulatory, ethnically diverse, urban population aged > or =55 yr. The goal of the study was to determine the number of fractures associated with hypovitaminosis D (< or =15 ng/mL serum 25-hydroxyvitamin D) and osteopenia (T-score <-1.5) by bone mineral density (BMD). From January 1 to July 31, 2001, we identified 262 persons who fractured in our community; 83 chose to enroll in the study. Enrolled patients had a BMD examination at two sites; their blood was drawn for 25-hydroxyvitamin D (25VitD), calcium, phosphorus, albumin, and alkaline phosphatase. At the completion of the study a letter was sent to the patients detailing the findings, and a copy sent to their physician. Of the 83 persons enrolled, 73 (88%) had evidence of osteopenia or osteoporosis (T-score <-1.5) and/or low 25VitD. All fractures in the community in person > or =55 yr, with or without a history of antecedent trauma, should be assessed with BMD and screening for 25VitD.

Language: en