Citation

Molinari M, Chiricozzi FR, Clausi S, Tedesco AM, De Lisa M, Leggio MG. Cerebellum 2008; 7(4): 611-615.

Affiliation

Experimental Neurorehabilitation and Ataxia Labs, IRCCS Santa Lucia Foundation, Rome, Italy. m.molinari@hsantalucia.it

Copyright

(Copyright © 2008, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s12311-008-0060-x

PMID

18941861

Abstract

The idea that cerebellar processing is required in a variety of cognitive functions is well accepted in the neuroscience community. Nevertheless, the definition of its role in the different cognitive domains remains rather elusive. Current data on perceptual and cognitive processing are reviewed with special emphasis on cerebellar sequencing properties. Evidences, obtained by neurophysiological and neuropsychological lesion studies, converge in highlighting comparison of temporal and spatial information for sequence detection as the key stone of cerebellar functioning across modalities. The hypothesis that sequence detection might represent the main contribution of cerebellar physiology to brain functioning is presented and the possible clinical significance in cerebellar-related diseases discussed.

Language: en