Citation

Centers for Disease Control and Prevention, USA. MMWR Morb. Mortal. Wkly. Rep. 2009; 58(48): 1345-1347.

Copyright

(Copyright © 2009, (in public domain), Publisher U.S. Centers for Disease Control and Prevention)

DOI

unavailable

PMID

20010509

Abstract

On November 18, 2008, the Nigerian Federal Ministry of Health (FMOH) received a report of 13 cases of unexplained acute renal failure among children from a hospital in Lagos state. Several of the patients had been exposed to a liquid acetaminophen-based teething medication. On November 21, officials from the Nigerian National Agency for Food and Drug Administration and Control (NAFDAC) discovered diethylene glycol (DEG) in four batches of the teething medication manufactured during August--October 2009. DEG is a toxic alcohol used in brake fluid, paint, and household cleaning products, and has been used illegally as a cheap substitute solvent in drug manufacturing. Previous DEG poisonings resulting from contamination of medications have been reported in the United States, Nigeria (1990), Panama, and other countries, and acute renal failure (ARF) is a known manifestation of DEG poisoning. An investigation was launched by the Nigeria Field Epidemiology and Laboratory Training Program (N-FELTP), CDC, and the Food and Drug Administration (FDA). This report summarizes the results of the investigation, which identified 57 cases of DEG poisoning among children aged

Language: en