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Citation |
Congdon P, Clarke T. Public Health 2005; 119(11): 1011-1015. |
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Affiliation |
Department of Geography, Queen Mary (University of London), Mile End Road, London E1 4NS, UK. |
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Copyright |
(Copyright © 2005, Elsevier Publishing) |
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DOI |
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PMID |
16084542 |
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Abstract |
This paper considers the assessment of the impact of a community-based randomized controlled trial to reduce repeat deliberate self-harm. It considers the drawbacks in simplistic applications of conventional significance testing procedures, as well as possible failures regarding the statistical assumptions underlying such tests. Instead, the paper considers how relevant prior information might be incorporated within a fully Bayesian-model-based assessment procedure. The model includes a latent trait approach to patient morbidity; controlling for morbidity and other patient characteristics enhances the impact of the intervention (measured by a hazard rate ratio). If allowance is made for external information (e.g. ethical approval of the treatment), the weight of evidence shifts towards a positive intervention effect. |