Citation

Coria C, Cabello A, Tassara E, Lopez E, Rosales H, Perez M, Zavala C, Muñoz P, Orellana G, Lnostroza MI, Contreras L, Kirsten L. Rev. Med. Chile 2009; 137(8): 1037-1044.

Vernacular Title

Efectos clinicos a largo plazo en ninos intoxicados con plomo en una region del

Affiliation

Servicios de Neurología, Facultad de Medicina, Universidad Católica de la Santísima Concepción (UCSC), Concepción, Chile.

Copyright

(Copyright © 2009, Sociedad Medica De Santiago)

DOI

/S0034-98872009000800006

PMID

19915767

Abstract

Background: In 1996 there was a massive lead poisoning in a southern rural community in Chile. The contamination source was a mill whose grinding stone was repaired with lead and contaminated the flour. Aim: To assess the presence of sequelae ten years later, among subjects that were exposed to lead on that occasion. Material and methods: Cross sectional study of 77 individuals (47 males), aged 10 to 25 years, that were exposed to lead in 1996 and were treated with EDTA. Results: Twenty one percent of subjects had a subnormal intellingence quotient (IQ). The risk of having a low IQ was significantly higher among those exposed before the age of six years. IQ was significantly lower among subjects that, immediately after the exposure, had a lead level over 48 fig/dl, compared with those that had a lead level below 43 fig/dl (86.7+/-7.3 and 93+/-11.6 respectively). No subjects with high blood pressure or evidences of nephrotoxicity were detected. Conclusions: Subjects aged inverted exclamation markess than six years at the moment of lead exposure had a lower IQ when assessed ten years later.

Language: es