Citation

Ray WA, Griffin MR, Malcolm E. Arch. Intern. Med. 1991; 151(4): 754-756.

Affiliation

Department of Preventive Medicine, Vanderbilt University School of Medicine, Nashville, Tenn 37232-2637.

Copyright

(Copyright © 1991, American Medical Association)

DOI

unavailable

PMID

2012459

Abstract

To determine whether cyclic antidepressants increase the risk of hip fracture, we conducted a population-based case-control study in the Canadian province of Saskatchewan. We identified 4501 persons 65 years of age or older with a first hospitalization for hip fracture between 1977 and 1985 and 24,041 comparable controls. Current antidepressant users had a relative risk of hip fracture of 1.6 (95% confidence interval, 1.3 to 1.9). Medical record review for a sample of 164 cases suggested this finding was not due to confounding by body mass, impaired ambulation, functional status, or dementia.

Language: en