Citation

Spoont MR. Psychol. Bull. 1992; 112(2): 330-350.

Affiliation

Department of Psychiatry, St. Paul Ramsey Medical Center, Minnesota 55101-2595.

Copyright

(Copyright © 1992, American Psychological Association)

DOI

unavailable

PMID

1454898

Abstract

Investigation of the role of 5-hydroxytryptophan (5-HT), which functions as a modulator in the central nervous system, across behavioral contexts suggests that a general principle of transmitter function may be derived that is independent of specific behaviors and specific neural loci. A functional principle of 5-HT action in neural information processing in the central nervous system is proposed. Extremes deviations in 5-HT activity result in biases in information processing that may have direct effects on behavior. Such biases may predispose to pathological conditions such as violent suicide and aggression.

Language: en