Citation

Jordan D, Borson-Chazot F, Veisseire M, Deluermoz S, Malicier D, Daléry J, Kopp N. J. Neural. Transm. 1992; 89(1-2): 103-110.

Affiliation

Laboratoire d'Anatomie Pathologique, Faculté de Médecine Carrel, France.

Copyright

(Copyright © 1992, Holtzbrinck Springer Nature Publishing Group)

DOI

unavailable

PMID

1418861

Abstract

The aim of the present study was to investigate the functional and/or pathological significance of the hemispherical lateralization of TRH using radioimmunoassay to determine the TRH concentration of nuclei and areas within the hypothalamus of suicide patients, with matching measurement being carried out on control subjects. In suicide patients, we found no significant difference in TRH concentration between the left and right intrahypothalamic structures, while the group used as control subjects (see Borson-Chazot, 1986) showed a significant left side predominance in the ventromedial nucleus, paraventricular nucleus and area dorsalis. As regards the TRH concentration in the right intrahypothalamic structures, no significant difference was found between the suicide patients and the control subjects. The absence of the left TRH predominance for the three intra-hypothalamic structures in question may be of pathological significance.

Language: en