Citation

Andorn AC. Brain Res. 1991; 568(1-2): 276-278.

Affiliation

Department of Psychiatry, Louisiana State University School of Medicine, Shreveport 71130.

Copyright

(Copyright © 1991, International Brain Research Organization, Publisher Elsevier Publishing)

DOI

unavailable

PMID

1667619

Abstract

Dysfunction in alpha-adrenergic receptor systems has been implicated to be of etiologic significance in depressive illness. The alpha 2-adrenergic ligand 3H.clonidine labels at least two sets of binding sites in normal human prefrontal cortex. We now report that the lower affinity component of 3H.clonidine binding is apparently absent in the prefrontal cortices of presumptive suicide victims.

Language: en