Citation

Richardson JS, Zaleski WA. Biol. Psychiatry 1983; 18(1): 99-101.

Copyright

(Copyright © 1983, Elsevier Publishing)

DOI

unavailable

PMID

6299409

Abstract

A 15-year-old male with a long history of self-mutilation resembling the Lesch-Nyhan syndrome, but with normal uric acid levels, was treated with naloxone. Pain-inducing behavior decreased in the evenings following infusion of the drug, and was markedly reduced for 2 days following the treatment period. Though not recommended as therapy, the observations suggest that naloxone may play a role in the regulation of endorphin/enkephalin neural systems.

Language: en