Citation

Hobi V, Kielholz P, Dubach UC. MMW Munch. Med. Wochenschr. 1981; 123(42): 1585-1588.

Vernacular Title

Die Wirkung von Bromazepam auf die Fahrtuchtigkeit.

Copyright

(Copyright © 1981, Verlagsgesellschaft OttoSpatz)

DOI

unavailable

PMID

6118830

Abstract

On 3 days (1, 8, 15) the acute (on day 1) and subacute (days 8 und 15) effects of bromazepam (Lexotanil) on variables of driving ability were studied in 55 young male medical students, randomly divided into 3 groups (placebo, 1.5 mg, 3.0 mg). The drug was well tolerated (no notable side effects). Dose-effects showed trends in group 3 (3.0 mg) with a stronger subjective impression of performance impairment which was, however, not confirmed by objective performance assessment, although time of reaction to optical stimuli was significantly longer after the 3 mg dose. In the discussion, it is pointed out that the results of this type of study in healthy subjects can only be regarded as indicative.

Language: de