Citation

Hindmarch I. Curr. Med. Res. Opin. 1976; 4(3): 197-206.

Copyright

(Copyright © 1976, Informa Healthcare)

DOI

10.1185/03007997609109303

PMID

949899

Abstract

A double-blind placebo-controlled crossover trial was carried out in 21 normal volunteers to study the effects of sub-chronic administration of clemastine on car driving ability and psychomotor performance. Subjects were assessed on 5 tests representing various aspects of everyday car driving experience, and on subjective rating scales for mood, sleep, and psychomotor integration. The results showed that repeated doses of 1 mg clemastine b.d. for 3 days had no significant consistent effect on any of the parameters measured.

Language: en