Citation

Cardish RJ. Can. J. Psychiatry 2007; 52(6 Suppl 1): 115S-127S.

Affiliation

Borderline Personality Disorder Clinic, Centre for Addiction and Mental Health, Toronto, Ontario. Robert_Cardish@camh.net

Copyright

(Copyright © 2007, Canadian Psychiatric Association, Publisher SAGE Publications)

DOI

unavailable

PMID

17824357

Abstract

OBJECTIVE: To review the evidence for the efficacy of pharmacotherapy and other biological treatments in suicidality associated with personality disorders, chiefly borderline personality disorder. METHOD: Systematic review of the literature. RESULTS: Studies evaluating treatment of suicidality in personality disorders are absent. However, several studies examine the efficacy of pharmacotherapy for core symptom clusters that are closely associated with suicidal behaviour. Efficacy exists with transient psychotic episodes, flashbacks and dissociations, affective dysregulation, impulsivity, and anger and hostility. CONCLUSIONS: Modest efficacy of pharmacologic treatments adjuvant to psychosocial treatments can be shown for clusters of symptoms related to borderline personality disorder.

Language: en