Citation

Muller-Oerlinghausen B. Psychiatr. Prax. 2007; 34(Suppl 3): S292-5.

Vernacular Title

Moglichkeiten medikamentoser Suizidpravention unter besonderer Berucksichtigung

Affiliation

Brain Center Berlin. bmoe@zedat.fu-berlin.de

Copyright

(Copyright © 2007, Georg Thieme Verlag)

DOI

10.1055/s-2007-970971

PMID

17786886

Abstract

OBJECTIVE: This minireview summarizes the existing evidence from large, international observational studies and RCTs on the suicide preventive effects of lithium as compared to other mood stabilizers and antidepressants. METHODS: Unsystematic literature review. RESULTS: There is increasing and robust evidence from a relatively large number of studies and metaanalyses that lithium long-term treatment reduces the suicide risk and overall mortality in patients with all kinds of depressive disorders (unipolar, bipolar, schizoaffective). Comparable evidence does not exist with regard to other mood stabilizers including atypical neuroleptics, or antidepressants. CONCLUSIONS: The existing evidence on the suicide preventive effect of lithium should be integrated in therapeutic guidelines and routine psychiatric care.

Language: de