Citation

Holtkamp K, Herpertz-Dahlmann B. Nervenarzt, Der 2008; 79(11): 1237-8, 1240, 1243-4, passim.

Vernacular Title

SSRI- und SNRI-Behandlung im Kindes- und Jugendalter. Aktuelle Informationen zum

Affiliation

DRK Fachklinik für Kinder- und Jugendpsychiatrie, Psychotherapie/Psychosomatik, Lindenstrasse 3-4, 53474, Bad Neuenahr, Germany. kholtkamp@web.de

Copyright

(Copyright © 2008, Holtzbrinck Springer Nature Publishing Group)

DOI

10.1007/s00115-008-2555-6

PMID

18958442

Abstract

The risk of suicidal thoughts and behaviours in the treatment of depressive children and adolescents with selective serotonin reuptake inhibitors (SSRI) and selective noradrenalin reuptake inhibitors (SNRI) is slightly but significantly elevated. These treatments in underage patients with anxiety or obsessive-compulsive disorders are however not related to a higher risk of suicidality. Effect sizes of SSRI/SNRI treatment in children and adolescents are medium to high in anxiety disorders (0.69), medium in obsessive-compulsive disorders (0.48), and low in depressive disorders (0.25). Nevertheless, the benefit:risk ratio is still positive in all three disorders.

Language: de