TY - JOUR PY - 2022// TI - The burden of mental disorders, substance use disorders and self-harm among young people in Europe, 1990-2019: findings from the Global Burden of Disease Study 2019 JO - Lancet regional health. Europe A1 - Castelpietra, Giulio A1 - Knudsen, Ann Kristin Skrindo A1 - Agardh, Emilie E. A1 - Armocida, Benedetta A1 - Beghi, Massimiliano A1 - Iburg, Kim Moesgaard A1 - Logroscino, Giancarlo A1 - Ma, Rui A1 - Starace, Fabrizio A1 - Steel, Nicholas A1 - Addolorato, Giovanni A1 - Andrei, Catalina Liliana A1 - Andrei, Tudorel A1 - Ayuso-Mateos, José L. A1 - Banach, Maciej A1 - Bärnighausen, Till Winfried A1 - Barone-Adesi, Francesco A1 - Bhagavathula, Akshaya Srikanth A1 - Carvalho, Felix A1 - Carvalho, Márcia A1 - Chandan, Joht Singh A1 - Chattu, Vijay Kumar A1 - Couto, Rosa A. S. A1 - Cruz-Martins, Natália A1 - Dargan, Paul I. A1 - Deuba, Keshab A1 - da Silva, Diana Dias A1 - Fagbamigbe, Adeniyi Francis A1 - Fernandes, Eduarda A1 - Ferrara, Pietro A1 - Fischer, Florian A1 - Gaal, Peter Andras A1 - Gialluisi, Alessandro A1 - Haagsma, Juanita A. A1 - Haro, Josep Maria A1 - Hasan, M. Tasdik A1 - Hasan, Syed Shahzad A1 - Hostiuc, Sorin A1 - Iacoviello, Licia A1 - Iavicoli, Ivo A1 - Jamshidi, Elham A1 - Jonas, Jost B. A1 - Joo, Tamas A1 - Jozwiak, Jacek Jerzy A1 - Katikireddi, Srinivasa Vittal A1 - Kauppila, Joonas H. A1 - Khan, Moien A. B. A1 - Kisa, Adnan A1 - Kisa, Sezer A1 - Kivimaki, Mika A1 - Koly, Kamrun Nahar A1 - Koyanagi, Ai A1 - Kumar, Manasi A1 - Lallukka, Tea A1 - Langguth, Berthold A1 - Ledda, Caterina A1 - Lee, Paul H. A1 - Lega, Ilaria A1 - Linehan, Christine A1 - Loureiro, Joana A. A1 - Madureira-Carvalho, Áurea M. A1 - Martinez-Raga, Jose A1 - Mathur, Manu Raj A1 - McGrath, John J. A1 - Mechili, Enkeleint A. A1 - Mentis, Alexios-Fotios A. A1 - Mestrovic, Tomislav A1 - Miazgowski, Bartosz A1 - Mirica, Andreea A1 - Mirijello, Antonio A1 - Moazen, Babak A1 - Mohammed, Shafiu A1 - Mulita, Francesk A1 - Nagel, Gabriele A1 - Negoi, Ionut A1 - Negoi, Ruxandra Irina A1 - Nwatah, Vincent Ebuka A1 - Padrón-Monedero, Alicia A1 - Panda-Jonas, Songhomitra A1 - Pardhan, Shahina A1 - Pasovic, Maja A1 - Patel, Jay A1 - Petcu, Ionela-Roxana A1 - Pinheiro, Marina A1 - Pollok, Richard Charles G. A1 - Postma, Maarten J. A1 - Rawaf, David Laith A1 - Rawaf, Salman A1 - Romero-Rodriguez, Esperanza A1 - Ronfani, Luca A1 - Sagoe, Dominic A1 - Sanmarchi, Francesco A1 - Schaub, Michael P. A1 - Sharew, Nigussie Tadesse A1 - Shiri, Rahman A1 - Shokraneh, Farhad A1 - Sigfusdottir, Inga Dora A1 - Silva, João Pedro A1 - Silva, Renata A1 - Socea, Bogdan A1 - Szócska, Miklós A1 - Tabarés-Seisdedos, Rafael A1 - Torrado, Marco A1 - Tovani-Palone, Marcos Roberto A1 - Vasankari, Tommi Juhani A1 - Veroux, Massimiliano A1 - Viner, Russell M. A1 - Werdecker, Andrea A1 - Winkler, Andrea Sylvia A1 - Hay, Simon I. A1 - Ferrari, Alize J. A1 - Naghavi, Mohsen A1 - Allebeck, Peter A1 - Monasta, Lorenzo SP - e100341 EP - e100341 VL - 16 IS - N2 - BACKGROUND: Mental health is a public health issue for European young people, with great heterogeneity in resource allocation. Representative population-based studies are needed. The Global Burden of Disease (GBD) Study 2019 provides internationally comparable information on trends in the health status of populations and changes in the leading causes of disease burden over time.

METHODS: Prevalence, incidence, Years Lived with Disability (YLDs) and Years of Life Lost (YLLs) from mental disorders (MDs), substance use disorders (SUDs) and self-harm were estimated for young people aged 10-24 years in 31 European countries. Rates per 100,000 population, percentage changes in 1990-2019, 95% Uncertainty Intervals (UIs), and correlations with Sociodemographic Index (SDI), were estimated.

FINDINGS: In 2019, rates per 100,000 population were 16,983 (95% UI 12,823 - 21,630) for MDs, 3,891 (3,020 - 4,905) for SUDs, and 89·1 (63·8 - 123·1) for self-harm. In terms of disability, anxiety contributed to 647·3 (432-912·3) YLDs, while in terms of premature death, self-harm contributed to 319·6 (248·9-412·8) YLLs, per 100,000 population. Over the 30 years studied, YLDs increased in eating disorders (14·9%;9·4-20·1) and drug use disorders (16·9%;8·9-26·3), and decreased in idiopathic developmental intellectual disability (-29·1%;23·8-38·5). YLLs decreased in self-harm (-27·9%;38·3-18·7). Variations were found by sex, age-group and country. The burden of SUDs and self-harm was higher in countries with lower SDI, MDs were associated with SUDs.

INTERPRETATION: Mental health conditions represent an important burden among young people living in Europe. National policies should strengthen mental health, with a specific focus on young people. FUNDING: The Bill and Melinda Gates Foundation.

Language: en

LA - en SN - 2666-7762 UR - http://dx.doi.org/10.1016/j.lanepe.2022.100341 ID - ref1 ER -