TY - JOUR PY - 2019// TI - [HIV, antiretroviral therapy and suicidal behaviour: a multidisciplinary case report and underlying neuroimmunological pathways] JO - Tijdschrift voor Psychiatrie A1 - Koolen, F. A1 - Schippers, J. A. A1 - Oude Lashof, A. M. L. A1 - Leue, C. SP - 57 EP - 61 VL - 61 IS - 1 N2 - The relationship between hiv, major depressive disorder and suicidal ideation is well established. For example, hiv-positive patients are seven times more likely to develop depression, and suicidal behaviour is also more prevalent. Antiretroviral therapy is known to further enhance these risks. We saw a 53-year-old patient with a depressive episode and suicidal ideation, possibly related to the use of dolutegravir/abacavir/lamivudine. We provide an overview of the literature and we present a neuro-immunological hypothesis for this psychiatric adverse event, which may occur even after months of treatment.
Language: nl
LA - nl SN - 0303-7339 UR - http://dx.doi.org/ ID - ref1 ER -