TY  - JOUR
PY  - 2020//
TI  - Equivalency of the diagnostic accuracy of the PHQ-8 and PHQ-9: a systematic review and individual participant data meta-analysis
JO  - Psychological medicine
A1  - Wu, Yin
A1  - Levis, Brooke
A1  - Riehm, Kira E.
A1  - Saadat, Nazanin
A1  - Levis, Alexander W.
A1  - Azar, Marleine
A1  - Rice, Danielle B.
A1  - Boruff, Jill
A1  - Cuijpers, Pim
A1  - Gilbody, Simon
A1  - Ioannidis, John P. A.
A1  - Kloda, Lorie A.
A1  - McMillan, Dean
A1  - Patten, Scott B.
A1  - Shrier, Ian
A1  - Ziegelstein, Roy C.
A1  - Akena, Dickens H.
A1  - Arroll, Bruce
A1  - Ayalon, Liat
A1  - Baradaran, Hamid R.
A1  - Baron, Murray
A1  - Bombardier, Charles H.
A1  - Butterworth, Peter
A1  - Carter, Gregory
A1  - Chagas, Marcos H.
A1  - Chan, Juliana C. N.
A1  - Cholera, Rushina
A1  - Conwell, Yeates
A1  - de Man-van Ginkel, Janneke M.
A1  - Fann, Jesse R.
A1  - Fischer, Felix H.
A1  - Fung, Daniel
A1  - Gelaye, Bizu
A1  - Goodyear-Smith, Felicity
A1  - Greeno, Catherine G.
A1  - Hall, Brian J.
A1  - Harrison, Patricia A.
A1  - Härter, Martin
A1  - Hegerl, Ulrich
A1  - Hides, Leanne
A1  - Hobfoll, Stevan E.
A1  - Hudson, Marie
A1  - Hyphantis, Thomas
A1  - Inagaki, Masatoshi
A1  - Jetté, Nathalie
A1  - Khamseh, Mohammad E.
A1  - Kiely, Kim M.
A1  - Kwan, Yunxin
A1  - Lamers, Femke
A1  - Liu, Shen-Ing
A1  - Lotrakul, Manote
A1  - Loureiro, Sonia R.
A1  - Lowe, Bernd
A1  - McGuire, Anthony
A1  - Mohd-Sidik, Sherina
A1  - Munhoz, Tiago N.
A1  - Muramatsu, Kumiko
A1  - Osório, Flavia L.
A1  - Patel, Vikram
A1  - Pence, Brian W.
A1  - Persoons, Philippe
A1  - Picardi, Angelo
A1  - Reuter, Katrin
A1  - Rooney, Alasdair G.
A1  - Santos, Iná S.
A1  - Shaaban, Juwita
A1  - Sidebottom, Abbey
A1  - Simning, Adam
A1  - Stafford, Lesley
A1  - Sung, Sharon
A1  - Tan, Pei Lin Lynnette
A1  - Turner, Alyna
A1  - van Weert, Henk C.
A1  - White, Jennifer
A1  - Whooley, Mary A.
A1  - Winkley, Kirsty
A1  - Yamada, Mitsuhiko
A1  - Benedetti, Andrea
A1  - Thombs, Brett D.
SP  - 1368
EP  - 1380
VL  - 50
IS  - 8
N2  - BACKGROUND: Item 9 of the Patient Health Questionnaire-9 (PHQ-9) queries about thoughts of death and self-harm, but not suicidality. Although it is sometimes used to assess suicide risk, most positive responses are not associated with suicidality. The PHQ-8, which omits Item 9, is thus increasingly used in research. We assessed equivalency of total score correlations and the diagnostic accuracy to detect major depression of the PHQ-8 and PHQ-9.  METHODS: We conducted an individual patient data meta-analysis. We fit bivariate random-effects models to assess diagnostic accuracy.  RESULTS: 16 742 participants (2097 major depression cases) from 54 studies were included. The correlation between PHQ-8 and PHQ-9 scores was 0.996 (95% confidence interval 0.996 to 0.996). The standard cutoff score of 10 for the PHQ-9 maximized sensitivity + specificity for the PHQ-8 among studies that used a semi-structured diagnostic interview reference standard (N = 27). At cutoff 10, the PHQ-8 was less sensitive by 0.02 (-0.06 to 0.00) and more specific by 0.01 (0.00 to 0.01) among those studies (N = 27), with similar results for studies that used other types of interviews (N = 27). For all 54 primary studies combined, across all cutoffs, the PHQ-8 was less sensitive than the PHQ-9 by 0.00 to 0.05 (0.03 at cutoff 10), and specificity was within 0.01 for all cutoffs (0.00 to 0.01).  CONCLUSIONS: PHQ-8 and PHQ-9 total scores were similar. Sensitivity may be minimally reduced with the PHQ-8, but specificity is similar.<p /> <p>Language: en</p>
LA  - en
SN  - 0033-2917
UR  - http://dx.doi.org/10.1017/S0033291719001314
ID  - ref1
ER  -