TY - JOUR PY - 2019// TI - Donepezil: an unusual therapy for acute diphenhydramine overdose JO - BMJ case reports A1 - Ahmad, Jamia A1 - Hasan, Md Jahidul A1 - Anam, Ahmad Mursel A1 - Barua, Dipesh Kumar SP - e226836 EP - e226836 VL - 12 IS - 3 N2 - An elderly man presented with the history of diphenhydramine hydrochloride overdose as a suicidal attempt. At presentation, he was in an acute confusional state with several anticholinergic features and had to be managed in intensive care unit. As an antidote for diphenhydramine hydrochloride, donepezil was used instead of physostigmine due to the unavailability of physostigmine in Bangladesh. The patient improved within the next 24 hours; his level of consciousness improved and the anticholinergic features regressed.

Language: en

LA - en SN - 1757-790X UR - http://dx.doi.org/10.1136/bcr-2018-226836 ID - ref1 ER -