TY  - JOUR
PY  - 2011//
TI  - Fatal intoxication due to brucine
JO  - Journal of analytical toxicology
A1  - Teske, Jorg
A1  - Weller, Jens-Peter
A1  - Albrecht, Urs-Vito
A1  - Fieguth, Armin
SP  - 248
EP  - 253
VL  - 35
IS  - 4
N2  - A sensitive method for identifying and quantifying brucine by means of liquid chromatography-tandem mass spectrometry is presented in this article. Based on a solid-phase extraction for human serum, the validation indicated limits of detection and quantification of 0.12 and 0.23 ng/mL, respectively. In one case of lethal suicidal brucine monointoxication, brucine concentrations of 1.51 μg/mL, 1.69 μg/mL, 9.94 μg/mL, 16.4 μg/g, 0.99 μg/g, 0.75 μg/g, and 1.95 mg/g were determined in femoral blood, urine, bile collected from the gallbladder, liver tissue, cerebellum, cerebrum, and stomach contents, respectively.<p /> <p>Language: en</p>
LA  - en
SN  - 0146-4760
UR  - http://dx.doi.org/10.1093/anatox/35.4.248
ID  - ref1
ER  -