TY  - JOUR
PY  - 1997//
TI  - Csf 5 - hiaa in violent and non-violent suicide attempters
JO  - Indian journal of psychiatry
A1  - Trivedi, J. K.
A1  - Pandey, S.
A1  - Dalal, P. K.
A1  - Dubey, M. P.
A1  - Sinha, P. K.
SP  - 41
EP  - 48
VL  - 39
IS  - 1
N2  - Many studies have reported involvement of monoamine neurotransmission in suicide through measurement of serotonin and its main metabolite, 5-HIAA, in brain of suicide victims and in CSF of suicide attempters. 23 non-depressed non-psychotic suicide attempters and equal number of controls were selected, and all the subjects were screened on Cornell Medical Index. Suicide attempters were assessed on Risk-Rescue Rating Scale and were divided into non-violent suicide attempters (N= 12) and violent suicide attempters (N= II). CSF of all subjects was collected by lumbar puncture and CSF 5-HIAA was measured by high performance liquid chromatography with electro-chemical detector. Risk-rescue rating score was significantly higher in violent suicide attempters as compared to non-violent suicide attempters. Mean CSF- 5- HIAA was significantly lower in suicide attempters as compared to normal controls. Mean CSF 5-HIAA was significantly lower in violent suicide attempters as compared to non-violent suicide attempters.<p /> <p>Language: en</p>
LA  - en
SN  - 0019-5545
UR  - http://dx.doi.org/
ID  - ref1
ER  -