TY  - JOUR
PY  - 2008//
TI  - A fatality involving 1,3-propanediol and its implications in measurement of other glycols
JO  - Journal of analytical toxicology
A1  - Garg, Uttam
A1  - Frazee, C. Clinton
A1  - Kiscoan, Mike
A1  - Scott, David
A1  - Peterson, Bonita
A1  - Cathcart, David
SP  - 324
EP  - 326
VL  - 32
IS  - 4
N2  - The decomposed body of a 45-year-old female was found, face down, in a mobile home, along with a suicide note and two antifreeze containers. Analysis of the body fluid collected from the decedent showed the presence of 58 mg/dL ethanol, but suspected ethylene glycol was not found in the sample. However, an unusually large peak of internal standard, 1,3-propanediol, was found in the sample. Gas chromatography-mass spectrometry analysis confirmed the presence of 1,3-propanediol in the sample. Using gas chromatography-flame-ionization detection, the concentration of 1,3-propanediol was determined to be 445 mg/dL. To our knowledge, this is the first report involving 1,3-propanediol as the cause of death. The study also highlights the importance for the close scrutiny of data, as 1,3-propanediol is a frequently used internal standard for the assay of glycols.<p /> <p>Language: en</p>
LA  - en
SN  - 0146-4760
UR  - http://dx.doi.org/10.1093/jat/32.4.324
ID  - ref1
ER  -