TY  - JOUR
PY  - 2006//
TI  - Major depression with psychosis after resection of a giant middle fossa hemangiopericytoma
JO  - Surgical Neurology
A1  - Sade, Burak
A1  - Budur, Kumar
A1  - Lee, Dae Kyu
A1  - Franco, Kathleen
A1  - Lee, Joung H.
SP  - 290
EP  - 292; discussion 292
VL  - 65
IS  - 3
N2  - BACKGROUND: Postoperative onset of acute major depression in a patient with no previous history of psychiatric disorder is highly unexpected after skull base surgery.  CASE DESCRIPTION: A 38-year-old woman with no previous physical or mental illness presented with a 3-month history of left ear pain, short-term memory disturbance, and motor dysphasia. Magnetic resonance imaging revealed a large extraaxial tumor in the left middle fossa. Left temporal craniotomy was performed, achieving complete tumor resection. The patient showed signs of confusion, disorientation, and severe depression 3 days after the surgery. She developed insomnia and auditory hallucinations along with expressed suicidal ideation, then deteriorated rapidly, necessitating a transfer to a psychiatric unit. In spite of the intensive treatment with antidepressive and antipsychotic medications, she continued to have prolonged psychotic symptoms and depression for several months after surgery.  CONCLUSION: Although the incidence is rare, psychiatric complications should be anticipated in patients undergoing resection of a large skull base tumor affecting the temporal lobe. The exact mechanism in this process is not clear; however, it is important to clinically differentiate treatable etiologies such as steroid-induced psychosis and postoperative delirium.<p /> <p>Language: en</p>
LA  - en
SN  - 0090-3019
UR  - http://dx.doi.org/10.1016/j.surneu.2005.06.041
ID  - ref1
ER  -