TY - JOUR PY - 2003// TI - Tissue distribution of xylazine in a suicide by hanging JO - Journal of analytical toxicology A1 - Moore, Karla A. A1 - Ripple, Mary G. A1 - Sakinedzad, Saffia A1 - Levine, Barry A1 - Fowler, David R. SP - 110 EP - 112 VL - 27 IS - 2 N2 - Xylazine (Rompun, Sedazine, AnaSed) is currently the most commonly used sedative-analgesic in veterinary medicine. There are nine published cases of xylazine's involvement in human drug-related deaths and impairment. However, blood concentrations were reported in only four of these cases. Three of these nine cases were fatalities involving xylazine, two of which involved xylazine alone but did not report blood concentrations because of extensive decomposition of the bodies. This report documents a case in which xylazine alone was identified in a suicide by hanging. The following xylazine concentrations were found: 2.3 mg/L in heart blood; 2.9 mg/L in peripheral (subclavian) blood; 6.3 mg/L in bile; 0.01 mg/L in urine; 6.1 mg/kg in liver; and 7.8 mg/kg in kidney.
Language: en
LA - en SN - 0146-4760 UR - http://dx.doi.org/10.1093/jat/27.2.110 ID - ref1 ER -