TY - JOUR PY - 1994// TI - [Carbamazepine poisoning: protracted course with development of intestinal atony and hepatic toxicity] JO - Wiener Klinische Wochenschrift A1 - Baischer, W. A1 - Wagner, A. A1 - Seidler, D. A1 - Musalek, M. A1 - Laggner, A. SP - 27 EP - 29 VL - 106 IS - 1 N2 - A 43 year-old female patient with a history of manic-depressive illness and prophylactic carbamazepine (CBZ) medication ingested a potentially lethal overdose of 20 g of the substance. Neurotoxic symptoms reached full intensity after about 24 hours. Subsequently, the patient developed a gastrointestinal atony, which proved to be refractory to treatment for several days. Moreover, there was an increase of bilirubin. Parallel to this we observed the persistence-and even intermittent re-increase--of toxic serum CBZ concentrations for one week with corresponding protracted clinical symptomatology.
Language: de
LA - de SN - 0043-5325 UR - http://dx.doi.org/ ID - ref1 ER -