TY  - JOUR
PY  - 1994//
TI  - Free-running psycho-physiologic circadians and three-month pattern in a woman isolated in a cave
JO  - New trends in experimental and clinical psychiatry
A1  - Hillman, D.C.
A1  - Siffre, M.
A1  - Milano, G.
A1  - Halberg, F.
SP  - 127
EP  - 133
VL  - 10
IS  - 3
N2  - In a woman isolated from society in a cave for 103 days, alterations of her time structures (chronomes) of several physiologic variables are recorded: awakening, 'to bed' eating, drinking, defecation, urination, the intermicturition interval, the rates of urinary water and creatinine excretion, the caffeine metabolite ratio, urine temperature and the estimation of 2 minutes. Sleep-wakefulness reveals a wobbly circadian component longer than 24 hours, transiently shortening in the middle of the isolation span. Some other variables also follow a pattern of wobbly circadian free-running. Beyond circadians, the time series of sparse around-the-clock two-minute estimations reveals further a 3-month cycle which, because of its length, is not replicated during the span of isolation from society. Any association between chronome alteration and a psychopathology, eventually associated with suicide, constitutes post hoc reasoning, yet an emotional depression has been found earlier in isolation from society for 2 months or more, albeit without ensuing suicide.<p /> <p>Language: en</p>
LA  - en
SN  - 0393-5310
UR  - http://dx.doi.org/
ID  - ref1
ER  -