TY  - JOUR
PY  - 2017//
TI  - Research Progress in Cell Apoptosis Induced by Shikonin and Signal Pathway of Apoptosis
JO  - Chinese Journal of Information on Traditional Chinese Medicine
A1  - Xie, Yu
A1  - Hou, Xiaolong
A1  - Wu, Chunlian
SP  - 125
EP  - 129
VL  - 
IS  - 12
N2  - s:Apoptosis, also known as programmed cell death, is a gene controlled active cell suicide process in order to maintain balance of organisms. Apoptosis is mainly mediated through three signal pathways, including the endoplasmic reticulum, mitochondria, and death receptor. As a kind of naphthoquinone compounds and one of the main active ingredients of Lithospermum, shikonin has many biological activities, and its anti-cancer research is recent hot spot. The anti-cancer mechanism of shikonin is closely related with apoptosis and three kinds of signaling pathways. This article reviewed the research progress in apoptosis and signal pathways induced by shikonin.<p /> <p>Language: zh</p>
LA  - zh
SN  - 1005-5304
UR  - http://dx.doi.org/10.3969/j.issn.1005-5304.2017.03.031
ID  - ref1
ER  -