TY  - JOUR
PY  - 2021//
TI  - Novel Magnetic Biosorbents, based on Chitosan Embedded Halloysite Nanotube; an Alternative Approach to Reduce Complications of Gastric Lavage in Suicidal Patients
JO  - Latin American Journal of Pharmacy
A1  - Majeed, S.
A1  - Shoaib, M.H.
A1  - Ahmad, F.R.
A1  - Mahmood, K.
A1  - Nisar, N.
A1  - Sohail, K.
A1  - Riaz, R.
A1  - Afzal, A.
A1  - Hanif, M.
SP  - 2873
EP  - 2882
VL  - 40
IS  - 12
N2  - Use of toxic concentration of para-phenylenediamines (PPD) for suicide has become a serious problem in all over the world, which can be reduced by preparing absorbable magnetic microspheres. The aim of present studies was to prepare three types of magnetic iron oxide (Fe3O4) adsorbents having chitosan (CTS), naturally occurring halloysite nanotubes (HNTs) and their combination by co-emulsion precipitation. Effect of different concentrations of CTS, HNTs and Fe3O4, their contact time with PPD, effect of different temperature and pH on adsorption were calculated. Magnetization was confirmed by vibrating sample manometer (VSM) which was ranged from 13.99 to 24.55 emu/g. Clear peaks of Fe and O was confirmed by energy dispersive X-ray spectroscopy (EDS). Interestingly, morphology of magnetic microspheres (FeHC7) was hollow spherical considered ideal for adsorption (1085.47 + 5.2 mg/g at 40 °C in pH 3.5) of PPD. Prepared FeHC7 microspheres can be considered as alternative approaches to reduce the complications of the gastric lavage in suicidal patients in emergency conditions. © 2021, Colegio de Farmaceuticos de la Provincia de Buenos Aires. All rights reserved.<p /> <p>Language: en</p>
LA  - en
SN  - 0326-2383
UR  - http://dx.doi.org/
ID  - ref1
ER  -