TY - JOUR PY - 2020// TI - SNI case of the week: Initial concomitant use of gabapentin, clonidine, and prednisone may enhance suicidal ideation: A case report JO - Surgical neurology international A1 - Ghaly, R.F. A1 - Plesca, A. A1 - Candido, K.D. A1 - Knezevic, N.N. SP - EP - VL - 11 IS - 41 N2 - BACKGROUND: Suicide cases are the end product of a combination of biological, clinical, psychological, social, and cultural risk/protective factors, and attempts to remain unpredictable. Case Description: A 43-year-old male presented to the hospital with jaundiced skin/eyes of 7 days' duration. He had a history of a major depressive disorder and chronic alcohol consumption (e.g., 3-5 alcoholic drinks/day for the past 15 years). Studies documented acute hepatic disease (e.g., biopsy-documented hepatocellular alcoholic hepatitis), accompanied by a cholestatic disease. The patient was discharged on clonidine, iron multivitamin, folic acid, gabapentin, and prednisone. Eight days postdischarge from the hospital, he committed suicide (e.g., self-inflicted gunshot wound to the head).

CONCLUSION: Concomitant administration of gabapentin, prednisone, and clonidine, especially if used for the first time, may play a synergistic effect in increasing a patient's suicide risk. © 2020 Scientific Scholar. All rights reserved.

Language: en

LA - en SN - 2229-5097 UR - http://dx.doi.org/10.25259/SNI_58_2020 ID - ref1 ER -